Have not tried IE yet, only Chrome (OSX and Windows 7) and FF on (OSX and Windows 7). I have not tried to clear the application cache... how would I do that?
Also, not to pick nits, but I am seeing this locally in dev and out on our staging server, so even if clearing the cache fixes it short-term, it is still an ongoing issue. Client will not be happy with that after dropping big $$$ on your top-end license.