Access Denied When Editing Image in Image Gallery

                    TempFile
Event Code :    SAVEFILETODISK
User       :    administrator

Description:    Message: Access to the path 'E:\HostingSpaces' is denied. 
Stack Trace: 
at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
at System.IO.Directory.InternalCreateDirectory(String fullPath, String path, Object dirSecurityObj, Boolean checkHost)

The Above error logged when i try to edit an image in image editor.

Path E:\HostingSpaces is the root folder that contains other web sites.

for example :E:\HostingSpaces\Website1.com\wwwroot

each site has its own dedicated application pool.

Witch permissions required for that folder to be applied.

NOTE : ONLY Image Editor Raise this error and any thing else works fine.