Hello Nicola,
You can define the size of an image in the particular function you will use for displaying images. You can use
<%# GetImage("Image", int width, int height) %> for instance (if the image is stored in
Direct uploader form control) and set the size to fit the thumbnail or some other functions depending on a form control which is used for those images.
Complete list of all available functions you can use in transformations can be found in
Context Help - Methods in transformations.
Best regards,
Filip Ligac